{"id":1699,"date":"2024-09-03T15:34:36","date_gmt":"2024-09-03T07:34:36","guid":{"rendered":"https:\/\/ktl.life.nthu.edu.tw\/lab\/?p=1699"},"modified":"2024-09-24T22:30:26","modified_gmt":"2024-09-24T14:30:26","slug":"our-research-on-cancer-metabolism-has-been-published-in-nature-communications","status":"publish","type":"post","link":"https:\/\/ktl.life.nthu.edu.tw\/lab\/2024\/09\/03\/our-research-on-cancer-metabolism-has-been-published-in-nature-communications\/","title":{"rendered":"Our research on cancer metabolism has been published in Nature Communications!"},"content":{"rendered":"\n

\u5f88\u958b\u5fc3\u5be6\u9a57\u5ba4\u7684\u7814\u7a76\u5167\u5bb9\u7d42\u7372\u767c\u8868<\/p>https:\/\/doi.org\/10.1038\/s41467-024-51875-9<\/strong><\/a><\/cite><\/blockquote><\/figure>\n\n\n\n

\u4ee5\u4e0b\u7c21\u4ecb\u4e00\u4e0b\u6211\u5011\u5728\u9019\u7bc7\u8ad6\u6587\u7684\u7814\u7a76\u5167\u5bb9<\/em><\/p><\/blockquote>\n\n\n\n

<\/p>\n\n\n\n

\n
\n
\"\"
\u5728\u816b\u7624\u5fae\u74b0\u5883\u4e2d\uff0c\u764c\u7d30\u80de\u6703\u900f\u904e\u91cb\u653e\u786b\u5316\u6c2b\u6539\u8b8a\u5176\u4ee3\u8b1d\u9014\u5f91\uff0c\u8b8a\u7684\u66f4\u611b\u5403\u7cd6\uff0c\u540c\u6642\u52a0\u901f\u5206\u88c2\u901f\u5ea6 (AI\u7e6a\u5716)\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n\n
\n
\"\"<\/figure>\n<\/div>\n<\/div>\n\n\n\n

\u5728\u764c\u7d30\u80de\u4e2d\uff0c\u65b0\u9673\u4ee3\u8b1d\u7684\u6539\u8b8a\u662f\u4fc3\u9032\u764c\u75c7\u9032\u5c55\u7684\u91cd\u8981\u56e0\u7d20\u3002\u6b63\u5e38\u7d30\u80de\u5728\u6c27\u6c23\u5145\u8db3\u7684\u74b0\u5883\u4e0b\uff0c\u6703\u9032\u884c\u6709\u6c27\u547c\u5438\uff0c\u5728\u7d30\u80de\u7684\u767c\u96fb\u5de5\u5ee0\u2014\u7c92\u7dda\u9ad4\u5167\u5229\u7528\u6c27\u6c23\u4f86\u7522\u751f\u5927\u91cf\u7684\u80fd\u91cf\uff1b\u800c\u5728\u6c27\u6c23\u4e0d\u8db3\u7684\u60c5\u6cc1\u4e0b\uff0c\u7d30\u80de\u5247\u6703\u9032\u884c\u767c\u9175\u4f5c\u7528\uff0c\u900f\u904e\u7d30\u80de\u8cea\u4e2d\u7684\u7cd6\u89e3\u4f5c\u7528\u7522\u751f\u5c11\u91cf\u80fd\u91cf\uff0c\u540c\u6642\u751f\u6210\u9152\u7cbe\u6216\u4e73\u9178\u3002\u7136\u800c\uff0c\u79d1\u5b78\u5bb6\u65e9\u5df2\u767c\u73fe\uff0c\u764c\u7d30\u80de\u5373\u4f7f\u5728\u6c27\u6c23\u5145\u8db3\u7684\u689d\u4ef6\u4e0b\uff0c\u4ecd\u7136\u50be\u5411\u4ee5\u7cd6\u89e3\u4f5c\u7528\u4f5c\u70ba\u4e3b\u8981\u4ee3\u8b1d\u65b9\u5f0f\uff0c\u9019\u4e00\u73fe\u8c61\u88ab\u7a31\u70ba\u74e6\u6c0f\u6548\u61c9\uff08Warburg Effect\uff09\u3002\u85c9\u7531\u9019\u7a2e\u4ee3\u8b1d\u6a5f\u5236\u7684\u8f49\u8b8a\uff0c\u764c\u7d30\u80de\u53ef\u4ee5\u7372\u5f97\u7cd6\u89e3\u4f5c\u7528\u7684\u4e2d\u9593\u7522\u7269\uff0c\u5f9e\u800c\u5408\u6210\u7d30\u80de\u5206\u88c2\u6240\u9700\u7684DNA\u3001RNA\u548c\u86cb\u767d\u8cea\uff0c\u4f7f\u5176\u80fd\u5920\u5feb\u901f\u589e\u751f\u3002<\/p>\n\n\n\n

\u764c\u7d30\u80de\u7684\u9019\u7a2e\u7279\u6b8a\u80fd\u91cf\u4ee3\u8b1d\u6a21\u5f0f\u4e00\u76f4\u4ee5\u4f86\u5f15\u8d77\u79d1\u5b78\u5bb6\u7684\u6975\u5927\u8208\u8da3\u3002\u66f4\u70ba\u91cd\u8981\u7684\u662f\uff0c\u79d1\u5b78\u5bb6\u5e0c\u671b\u80fd\u5920\u901a\u904e\u5f15\u5c0e\u764c\u7d30\u80de\u6062\u5fa9\u6b63\u5e38\u7684\u6709\u6c27\u547c\u5438\u4f86\u5207\u65b7\u5176\u80fd\u91cf\u4f9b\u61c9\uff0c\u5f9e\u800c\u963b\u6b62\u764c\u7d30\u80de\u7684\u589e\u751f\u3002\u70ba\u6b64\uff0c\u79d1\u5b78\u5bb6\u5011\u62c6\u89e3\u7cd6\u89e3\u4f5c\u7528\u7684\u4e0b\u6e38\u4f9b\u61c9\u93c8\uff0c\u5e0c\u671b\u5f9e\u4e2d\u627e\u51fa\u6700\u70ba\u91cd\u8981\u7684\u4e0b\u6e38\u5206\u5b50\u3002\u5728\u9019\u5176\u4e2d\uff0c\u79d1\u5b78\u5bb6\u767c\u73fe\uff0c\u4e19\u916e\u9178\u6fc0\u9176PKM2\u7684\u6d3b\u6027\u6700\u70ba\u95dc\u9375\u3002\u800c\u6b64\u6b21\uff0c\u6211\u5011\u7684\u7814\u7a76\u767c\u73fe\uff0c\u5728\u816b\u7624\u5167\u7684\u60e1\u52a3\u74b0\u5883\u4e2d\uff0c\u7f3a\u6c27\u6703\u5c0e\u81f4\u786b\u5316\u6c2b\u7684\u751f\u6210\uff0c\u800c\u786b\u5316\u6c2b\u662f\u4e00\u7a2e\u7531\u8eab\u9ad4\u81ea\u7136\u7522\u751f\u7684\u6c23\u9ad4\u8a0a\u865f\u5206\u5b50\u3002\u786b\u5316\u6c2b\u900f\u904e\u86cb\u767d\u5f8c\u4fee\u98fe\u6539\u8b8a\u4e86PKM2\u7684\u86cb\u767d\u7d50\u69cb\uff0c\u5f9e\u800c\u6539\u8b8a\u5176\u6d3b\u6027\uff0c\u4fc3\u9032\u764c\u7d30\u80de\u7684\u7cd6\u4ee3\u8b1d\uff0c\u4f7f\u5176\u651d\u53d6\u66f4\u591a\u7684\u8461\u8404\u7cd6\u9032\u884c\u7cd6\u89e3\u4f5c\u7528\uff0c\u4e26\u8fc5\u901f\u589e\u751f\u3002<\/p>\n\n\n\n

\u6211\u5011\u627e\u5230\u4e86\u786b\u5316\u6c2b\u5728PKM2\u4e0a\u7684\u4fee\u98fe\u4f4d\u9ede\uff0c\u4e26\u767c\u73fe\u5982\u679c\u963b\u6b62\u786b\u5316\u6c2b\u5c0d\u9019\u4e00\u4f4d\u9ede\u7684\u4fee\u98fe\uff0c\u5c31\u80fd\u6539\u8b8a\u764c\u7d30\u80de\u7279\u6709\u7684\u7cd6\u4ee3\u8b1d\u9014\u5f91\uff0c\u5f15\u5c0e\u764c\u7d30\u80de\u6062\u5fa9\u6b63\u5e38\u7684\u6709\u6c27\u547c\u5438\uff0c\u4e26\u5207\u65b7\u5176\u4e2d\u9593\u7522\u7269\u7684\u4f9b\u61c9\uff0c\u9032\u800c\u963b\u6b62\u764c\u7d30\u80de\u7684\u589e\u751f\u3002\u5718\u968a\u9032\u4e00\u6b65\u5229\u7528\u4e73\u764c\u7d30\u80de\u7684\u5c0f\u9f20\u81f4\u764c\u6a21\u578b\uff0c\u8b49\u5be6\u4e86\u963b\u6b62\u786b\u5316\u6c2b\u4fee\u98fePKM2\u53ef\u4ee5\u6709\u6548\u6291\u5236\u4e73\u764c\u7684\u751f\u9577\u3002\u6b64\u9805\u7814\u7a76\u767c\u73fe\u7684\u6297\u764c\u7b56\u7565\uff0c\u82e5\u80fd\u9032\u4e00\u6b65\u767c\u5c55\u70ba\u85e5\u7269\uff0c\u4e0d\u50c5\u53ef\u61c9\u7528\u65bc\u4e73\u764c\u6cbb\u7642\uff0c\u9084\u6709\u671b\u61c9\u7528\u65bc\u5176\u4ed6\u764c\u75c7\u7684\u6cbb\u7642\u3002 \u672c\u7814\u7a76\u7531\u6e05\u83ef\u5927\u5b78\u751f\u91ab\u5b78\u9662\u7684\u6797\u6137\u608c\u3001\u912d\u60e0\u6625\u3001\u738b\u96ef\u975c\u548c\u738b\u6167\u83c1\u8001\u5e2b\u7d44\u6210\u7684\u8de8\u9818\u57df\u5718\u968a\u9032\u884c\uff0c\u4e26\u8207\u4e2d\u570b\u91ab\u85e5\u5927\u5b78\u7684\u738b\u9678\u6d77\u9662\u58eb\u548c\u53f0\u5317\u91ab\u5b78\u5927\u5b78\u7684\u9f94\u884c\u5065\u9662\u58eb\u5408\u4f5c\uff0c\u5f9e\u4ee3\u8b1d\u91ab\u5b78\u7684\u89d2\u5ea6\u7d50\u5408\u7d50\u69cb\u751f\u7269\u5b78\u7684\u5206\u5b50\u6a5f\u5236\uff0c\u627e\u51fa\u4e86\u91cd\u8981\u7684\u764c\u75c7\u6cbb\u7642\u95dc\u9375\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u5f88\u958b\u5fc3\u5be6\u9a57\u5ba4\u7684\u7814\u7a76\u5167\u5bb9\u7d42\u7372\u767c\u8868 https:\/\/doi.or …<\/p>\n","protected":false},"author":1,"featured_media":1701,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[16,17],"tags":[],"_links":{"self":[{"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/posts\/1699"}],"collection":[{"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/comments?post=1699"}],"version-history":[{"count":11,"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/posts\/1699\/revisions"}],"predecessor-version":[{"id":1715,"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/posts\/1699\/revisions\/1715"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/media\/1701"}],"wp:attachment":[{"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/media?parent=1699"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/categories?post=1699"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/tags?post=1699"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}