{"id":2,"date":"2023-01-05T14:57:40","date_gmt":"2023-01-05T06:57:40","guid":{"rendered":"http:\/\/140.114.98.112\/wordpress\/?page_id=2"},"modified":"2023-01-09T19:48:59","modified_gmt":"2023-01-09T11:48:59","slug":"research","status":"publish","type":"page","link":"https:\/\/ktl.life.nthu.edu.tw\/lab\/research\/","title":{"rendered":"Research"},"content":{"rendered":"\n<h2 class=\"has-text-align-center wp-block-heading\">Research Interests<\/h2>\n\n\n\n<p>Cancer is the most common cause of death in Taiwan, and researchers have estimated that metastasis is responsible for about 90% of cancer-related deaths. However, therapies specifically used to target cancer metastasis are severely limited. Metastasis is a sequence of multiple steps, including invasion from the primary tumor, intravasation, transport, extravasation, and colonization at distant organs. In my lab, our major focus is to identify potential molecules that are involved in the regulation of cancer metastasis, cancer metabolism, tumor microenvironment, and precision medicine. Our goal is to conduct research related to the translational medicine and to collaborate with experts from different fields to decipher the underlying mechanisms of those molecules we identified. To achieve the goal, my lab focuses on four major directions as listed below:<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><a href=\"https:\/\/ktl.life.nthu.edu.tw\/lab\/2023\/01\/07\/cancer-metastasis\/\"><img loading=\"lazy\" decoding=\"async\" width=\"346\" height=\"307\" src=\"http:\/\/ktl.life.nthu.edu.tw\/lab\/wp-content\/uploads\/2023\/01\/Research-1.png\" alt=\"\" class=\"wp-image-1242\" srcset=\"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-content\/uploads\/2023\/01\/Research-1.png 346w, https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-content\/uploads\/2023\/01\/Research-1-300x266.png 300w\" sizes=\"auto, (max-width: 346px) 100vw, 346px\" \/><\/a><figcaption><strong>Metastasis<\/strong><br>Identification of Therapeutic Targets to Suppress Cancer Cell Migration &amp; Invasion<\/figcaption><\/figure><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><a href=\"https:\/\/ktl.life.nthu.edu.tw\/lab\/2023\/01\/07\/hydrogen-sulfide-modulation-in-cell-metabolism\/\"><img loading=\"lazy\" decoding=\"async\" width=\"346\" height=\"305\" src=\"http:\/\/ktl.life.nthu.edu.tw\/lab\/wp-content\/uploads\/2023\/01\/Research-2.png\" alt=\"\" class=\"wp-image-1243\" srcset=\"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-content\/uploads\/2023\/01\/Research-2.png 346w, https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-content\/uploads\/2023\/01\/Research-2-300x264.png 300w\" sizes=\"auto, (max-width: 346px) 100vw, 346px\" \/><\/a><figcaption><strong>Metabolism<\/strong><br>Hydrogen Sulfide Modulation in Cell Metabolism<\/figcaption><\/figure><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><a href=\"https:\/\/ktl.life.nthu.edu.tw\/lab\/2023\/01\/07\/cross-talk-between-cancer-cells-and-macrophages-in-the-tumor-microenvironment\/\"><img loading=\"lazy\" decoding=\"async\" width=\"345\" height=\"306\" src=\"http:\/\/ktl.life.nthu.edu.tw\/lab\/wp-content\/uploads\/2023\/01\/Research-3.png\" alt=\"\" class=\"wp-image-1244\" srcset=\"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-content\/uploads\/2023\/01\/Research-3.png 345w, https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-content\/uploads\/2023\/01\/Research-3-300x266.png 300w\" sizes=\"auto, (max-width: 345px) 100vw, 345px\" \/><\/a><figcaption><strong>Microenvironment<\/strong><br>Identification of Key Players Involved in the Cross-talk Between Cancer Cells and Macrophages in the Tumor Microenvironment<\/figcaption><\/figure><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><a href=\"https:\/\/ktl.life.nthu.edu.tw\/lab\/2023\/01\/07\/microrna-based-therapy-in-precision-cancer-medicine\/\"><img loading=\"lazy\" decoding=\"async\" width=\"343\" height=\"305\" src=\"http:\/\/ktl.life.nthu.edu.tw\/lab\/wp-content\/uploads\/2023\/01\/Research-4.png\" alt=\"\" class=\"wp-image-1245\" srcset=\"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-content\/uploads\/2023\/01\/Research-4.png 343w, https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-content\/uploads\/2023\/01\/Research-4-300x267.png 300w\" sizes=\"auto, (max-width: 343px) 100vw, 343px\" \/><\/a><figcaption><strong>Precision Medicine<\/strong><br>Targeting Oncogenes by microRNA-based precision Therapy<\/figcaption><\/figure><\/div>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"has-text-align-center wp-block-heading\">\u7814\u7a76\u8208\u8da3 (\u4e2d\u6587\u77ed\u7248)<\/h2>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" 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Interests Cancer is t &#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-2","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/pages\/2","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/comments?post=2"}],"version-history":[{"count":17,"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/pages\/2\/revisions"}],"predecessor-version":[{"id":1435,"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/pages\/2\/revisions\/1435"}],"wp:attachment":[{"href":"https:\/\/ktl.life.nthu.edu.tw\/lab\/wp-json\/wp\/v2\/media?parent=2"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}